Show Summary Details
Page of

Management of Melanoma Brain Metastases 

Management of Melanoma Brain Metastases
Management of Melanoma Brain Metastases

Solmaz Sahebjam

, Nikhil G. Rao

, and Peter A. Forsyth

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 13 July 2020

Melanoma commonly metastasizes to the brain and central nervous system (CNS); CNS metastases occur in more than half of patients with advanced melanoma. This remarkable neurotropism has not yet been explained. The prognosis of patients with melanoma brain metastasis remains grim, and the median overall survival after diagnosis of brain metastases is only two to nine months. This chapter asserts that the optimal management of melanoma brain metastasis patients requires the multidisciplinary collaboration of neurosurgeons, radiation oncologists, neuro-oncologists, and medical oncologists to tailor the treatment plan based on the clinical condition of the patient and the molecular characteristics of the tumor. Ideally this should be done in a dedicated melanoma brain metastases clinic. This chapter discusses each of the individual treatment modalities.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.