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Inflammatory and Noninflammatory Arthritis 

Inflammatory and Noninflammatory Arthritis
Chapter:
Inflammatory and Noninflammatory Arthritis
Author(s):

Clement J. Michet

DOI:
10.1093/med/9780199948949.003.0024
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date: 17 January 2020

Rheumatoid arthritis is a chronic systemic inflammatory disease characterized by joint destruction. It affects 0.03% to 1.5% of the population worldwide. Women are affected 3 times more frequently than men. Osteoarthritis is the failure of articular cartilage and subsequent degenerative changes in subchondral bone, bony joint margins, synovium, and para-articular fibrous and muscular structures. Osteoarthritis is the most common rheumatic disease; 80% of patients have some limitation of their activities, and 25% are unable to perform major activities of daily living. This chapter has two goals: review the diagnosis, clinical features, complications, and treatment of rheumatoid arthritis and other rheumatoid disorders and review the diagnosis, clinical features, and treatment of osteoarthritis and its clinical subsets.

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