Show Summary Details
Page of

AMH/MIS and Its Receptors: The Persistent Müllerian Duct Syndrome 

AMH/MIS and Its Receptors: The Persistent Müllerian Duct Syndrome
AMH/MIS and Its Receptors: The Persistent Müllerian Duct Syndrome

Jean-Yves Picard

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2021. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 24 February 2021

Antimüllerian hormone (AMH), also called müllerian inhibiting substance (MIS), is a member of the transforming growth factor-β‎ (TGF-β‎) family, produced exclusively by the gonads, that plays an important role in sex differentiation and gonadal function. Its action involves WNT inhibitory factor 1 (Wif2; Park, et al, 2014). Mutations in either the hormone or its receptor lead to persistent mullerian derivatives causing crpyptorchidism. Male sterility is frequent even when testes are lowered early.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.