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AXIN1 and Caudal Duplication Anomaly 

AXIN1 and Caudal Duplication Anomaly
AXIN1 and Caudal Duplication Anomaly

Christine R. Zhang

and Suyinn Chong

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date: 27 February 2021

Caudal duplication anomaly involves multiple congenital abnormalities with hallmark duplication of the distal organs. The affected systems vary from case to case, but often include the gastrointestinal tract, urogenital tract and spinal cord. Caudal duplication anomaly is sporadic and, at present, its pathogenesis remains unclear. Some studies have implicated the involvement of genetic and/or epigenetic changes at the axis inhibition, AXIN, gene (Kroes, Takahashi et al. 2002; Oates, van Vliet et al. 2006).

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