Show Summary Details
Page of

Bronchiectasis: Comorbid, Coexisting, and Differential Diagnosis 

Bronchiectasis: Comorbid, Coexisting, and Differential Diagnosis
Bronchiectasis: Comorbid, Coexisting, and Differential Diagnosis

Nizar Naji

and Paul M. O’Byrne

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2021. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 23 April 2021

Bronchiectasis is one of the most debilitating chronic respiratory diseases, which affects all ages, with significant morbidity and mortality. It is recognized clinically by chronic persistent daily cough, productive of mucopurulent sputum. The defining characteristic is the permanent abnormal dilatation and destruction of bronchial walls, which involve both the major bronchi and bronchioles. It is a major contributor to progressive lung function decline and functional disability, especially in patients with respiratory comorbidities. Bronchial hygiene, to clear airway secretions, is the basis of management. Bronchodilators and fixed-dose combination therapy with an inhaled corticosteroid and a long-acting β‎-agonist provide clinical benefit, but do not reduce the risks for acute exacerbations. The airways of patients with bronchiectasis are often colonized with pathologic bacteria, and acute exacerbations require antibiotic therapy. Allergic bronchopulmonary aspergillosis often requires daily oral corticosteroids for management.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.