Show Summary Details
Page of

Nasal Polyps and Chronic Rhinosinusitis: Comorbid 

Nasal Polyps and Chronic Rhinosinusitis: Comorbid
Chapter:
Nasal Polyps and Chronic Rhinosinusitis: Comorbid
Author(s):

Hae-Sim Park

, Mario Sánchez-Borges

, Seung Youp Shin

, and Marek L. Kowalski

DOI:
10.1093/med/9780199918065.003.0021
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2021. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 09 May 2021

Chronic rhinosinusitis (CRS) and nasal polyp (NP) are major comorbid conditions of bronchial asthma. CRS with NP (CRSwNP) occurs in the setting of CRS characterized by TH2 and eosinophilic inflammation. Therefore, CRSwNP is considered an entity separate from CRS without NP (CRSsNP). Previous studies demonstrated a strong association between asthma and CRS, and patients with asthma and CRS are more likely to have NP. The presence of CRSwNP can increase asthma severity, and effective medical management can improve asthma outcomes, including overall lung function and asthma control, and drug requirements. Surgery should be reserved for select patients with inadequate response to medical management or medication intolerance or side effects. Future research may further elucidate the pathophysiology of CRS and NP, which may in turn lead to development of more effective treatment modalities.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.