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Occupational Asthma: Comorbid and Differential Diagnosis 

Occupational Asthma: Comorbid and Differential Diagnosis
Occupational Asthma: Comorbid and Differential Diagnosis

Manon Labrecque

, Roberto Castaño

, Grégory Moullec

, Ignacio Ansottegui

, and Denyse Gautrin

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date: 09 May 2021

Work-related asthma can be divided in two major entities: work-exacerbated asthma and occupational asthma. Occupational asthma is further split into two subtypes: sensitizer-induced occupational asthma and irritant-induced asthma, which includes reactive airway dysfunction syndrome. The patient’s medical history (type of symptoms and timing) is not sufficient to diagnose occupational asthma. The diagnosis requires an objective confirmation of asthma and of work-related functional changes. Psychological distress, health-related quality-of-life impairment, and comorbid psychiatric disorder are frequent in patients with work-related asthma or work-related asthma symptoms and have to be considered in the evaluation and treatment. Many areas of research are still needed to understand the complexity of work-related asthma.

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