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Bioinformatics, Systems Biology, and Systems Medicine 

Bioinformatics, Systems Biology, and Systems Medicine
Chapter:
Bioinformatics, Systems Biology, and Systems Medicine
Author(s):

Binay Panda

and Neeraja M. Krishnan

DOI:
10.1093/med/9780199896028.003.0006
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date: 30 October 2020

Bioinformatics is an inter-disciplinary approach that broadly aims at applying computational power and analytical skills to solve biological problems. It is now a recognized component of the computational biology leading the way forward for systems biology. Systems biology attempts to map out the complexity of interactions among individual components, rather than reduce its complexity by elimination of parts as in classical genetics and integrates concepts of theoretical biology with experimental validation. Systems biology & systems medicine are heavily dependent on high-throughput data and bioinformatics analyses. Whole process includes high-throughput data generation, downstream analyses and interpretation with a focus on data generated by the newer generations of DNA sequencers. The ultimate aim of bioinformatics application is the description on biological structure and function along with its utility in clinical effectiveness. This, along with the need to understand and apply genome science to medicine, is making computational biology indispensable to scientists involved in genome medicine and systems biology research.

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