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Biobanking for Genomics-Based Translational Medicine 

Biobanking for Genomics-Based Translational Medicine
Chapter:
Biobanking for Genomics-Based Translational Medicine
Author(s):

Steven J. Madore

DOI:
10.1093/med/9780199896028.003.0015
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date: 30 October 2020

The engines driving the development of new and better approaches and technologies resulting in advancing the “bench-to-bedside” paradigm of translational medicine are basic and clinical research. Key discoveries rely on several factors, including solid experimental design, relevant in vitro and in vivo models, and new technological advancements, as well as the ready availability of high quality, well annotated biospecimens. Sources for such valuable biological samples are biobanks or biorepositories. The term “biobank” is the general term for a repository of biological samples or biospecimens. Biobanks add significant value and integrity to samples given that sample collection, annotation, processing and storage are executed according to well-established and standardized procedures. Bioiobanks offer researchers a “one-stop shopping” resource for useful biological samples. The importance of biospecimen resources is widely acknowledged in both scientific and lay world. This chapter introduces the concept of biobanking science and discuss the importance of these repositories as contributors to translational research, as well as highlight some of the challenges associated with biospecimens as material for analysis by genomic technologies.

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