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Neuroanatomy of Specific Reading Disabilities IV: Functional Magnetic Resonance Imaging 

Neuroanatomy of Specific Reading Disabilities IV: Functional Magnetic Resonance Imaging
Chapter:
Neuroanatomy of Specific Reading Disabilities IV: Functional Magnetic Resonance Imaging
Author(s):

Yitzchak Frank

DOI:
10.1093/med/9780199862955.003.0008
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date: 17 January 2020

Advantages of functional magnetic resonance imaging (fMRI) over positron emission tomography (PET) include a higher spatial and temporal resolution, and the fact that there is no need for an injection of a radionuclide isotope, meaning no radiation exposure. The latter is especially important for studies designed for children and adolescents. The fMRI signal changes when deoxygenated blood is replaced by oxygenated blood. It changes by a small amount in regions that are activated by a stimulus or a task, as a result of the combined effects of increase in the tissue blood flow, volume, and oxygenation. The methods used to record the changes (such as echo-planar imaging) are methods that can provide images at a rate fast enough to capture the time course of the hemodynamic response to neural activation.

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