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Neuroanatomy of Specific Reading Disabilities III: Diffusion Tensor Imaging 

Neuroanatomy of Specific Reading Disabilities III: Diffusion Tensor Imaging
Neuroanatomy of Specific Reading Disabilities III: Diffusion Tensor Imaging

Yitzchak Frank

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date: 18 January 2020

Diffusion tensor imaging (DTI) is a neuroimaging method that provides information about the degree and direction of water diffusion within individual voxels of the magnetic resonance image, providing clues to the structure of the tissues. Neuroimaging with DTI is based on the fact that diffusion is isotropic (equal in all directions) in cerebral spinal fluid and cell bodies but anisotropic (greater in one direction than the other directions) in the white matter (which is comprised of myelinated axons, organized into fiber bundles). In cerebral gray matter, internal cellular structures and cell membranes slow the rate of diffusion in comparison with the rate in cerebral spinal fluid, but diffusion remains isotropic (equal in all directions). In white matter, cell structure impedes the rate of diffusion perpendicular to the directional orientation of the axon fibers, while leaving the rate of diffusion parallel to the axon relatively unhindered.

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