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Histoplasma capsulatum 

Histoplasma capsulatum
Chapter:
Histoplasma capsulatum
Author(s):

Janis E. Blair

DOI:
10.1093/med/9780199827626.003.0015
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date: 09 July 2020

Histoplasmosis is caused by Histoplasma capsulatum, one of the most common opportunistic infections in persons with AIDS. Varieties include Histoplasma capsulatum var capsulatum and Histoplasma capsulatum var duboisii (Histoplasma duboisii).

Histoplasma capsulatum var capsulatum causes histoplasmosis in the Americas, parts of Africa, eastern Asia, and Australia rarely, in Europe. Histoplasma capsulatum var duboisii (Histoplasma duboisii) causes African histoplasmosis, which occurs only in Africa between the Tropic of Cancer and the Tropic of Capricorn and on the island of Madagascar. It manifests as a subacute granuloma of the skin or bone but may disseminate to the skin, lymph nodes, bones, joints, lungs, and abdomen.

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