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Infection and antibiotic management 

Infection and antibiotic management
Chapter:
Infection and antibiotic management
Author(s):

Jeffrey A. Claridge

and Aman Banerjee

DOI:
10.1093/med/9780199777709.003.0018
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date: 10 April 2020

Nosocomial infections are a major patient safety issue in the ICU. They causesignificant increases in patient morbidity and mortality, as well as increase medicalexpenses. Trauma patients often sustain multiple injuries—any of which canlead to infection. Critically ill trauma patients have a higher risk of infectioncompared to other surgical ICU cohorts. Trauma patientshave higher rates of emergency procedures such as intubation, central venouscatheterization, and tube thoracostomy, where the use of sterile techniquemight not be absolute. Trauma and blood transfusion may also be associatedwith immunosuppression. Additionally, trauma ICU device utilization rates areamong the highest when compared to other ICU types.

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