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Acute kidney injury 

Acute kidney injury
Chapter:
Acute kidney injury
Author(s):

Greta L. Piper

and Lewis J. Kaplan

DOI:
10.1093/med/9780199777709.003.0016
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date: 22 February 2020

AKI is increasingly common and continues to be associated with significantmorbidity and mortality. Although the understanding of certain etiologies andmechanisms has improved, the general diagnostic approach remains unchanged.Prevention of initial AKI, as well as prevention of worsening of AKI with supportivetherapy, remains the most effective means of managing this insult.Classification of kidney injury with the RIFLE criteria provides a common referencefor comparison that can be used for future trials to further elucidateprognosis as well as provide more standardized evidence-based protocols fortreatment.

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