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Soft tissue trauma and rhabdomyolysis 

Soft tissue trauma and rhabdomyolysis
Soft tissue trauma and rhabdomyolysis

Paula Ferrada

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date: 22 February 2020

Rhabdomyolysis is the breakdown of muscle fibers with leakage of intracellularcontents into the systemic circulation. The result of this extracellular rush of intracellular contents is multi-systemic. One of the devastating consequences ofthis disease is renal failure. This is due to decreased renal perfusion, cast formationwith tubular obstruction, and the direct toxic effects of myoglobin on therenal tubules. Trauma, particularly crush injury, is the most common predisposingfactor for this disease. Any patient with crush injury or/and a large amount of muscle compromisefrom soft tissue injury must be treated for rhabdomyolysis until provenotherwise.

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