Show Summary Details
Page of

Soft tissue trauma and rhabdomyolysis 

Soft tissue trauma and rhabdomyolysis
Chapter:
Soft tissue trauma and rhabdomyolysis
Author(s):

Paula Ferrada

DOI:
10.1093/med/9780199777709.003.0010
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 22 February 2020

Rhabdomyolysis is the breakdown of muscle fibers with leakage of intracellularcontents into the systemic circulation. The result of this extracellular rush of intracellular contents is multi-systemic. One of the devastating consequences ofthis disease is renal failure. This is due to decreased renal perfusion, cast formationwith tubular obstruction, and the direct toxic effects of myoglobin on therenal tubules. Trauma, particularly crush injury, is the most common predisposingfactor for this disease. Any patient with crush injury or/and a large amount of muscle compromisefrom soft tissue injury must be treated for rhabdomyolysis until provenotherwise.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.