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Aging Changes and Pharmacotherapy Principles 

Aging Changes and Pharmacotherapy Principles
Chapter:
Aging Changes and Pharmacotherapy Principles
Author(s):

Tanya Fabian

DOI:
10.1093/med/9780199765782.003.0004
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date: 05 December 2020

Chapter 4 provides an overview of the physiological changes that occur with aging and the impact of these changes on pharmacokinetics and pharmacodynamics, and discusses the increased risk for adverse events, as well as the presence of comorbid medical and psychiatric illness that may present in elderly patients.Drug-drug interactions that are common in the elderly, and additional pharmacotherapy complications in the geriatric population are also discussed, including challenges of polypharmacy, non-adherence and the increasing use of over the counter and herbal supplements, including medications not recommended for use in the elderly.

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