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Anaphylaxis 

Anaphylaxis
Chapter:
Anaphylaxis
Author(s):

Liana G Hosu

and Lori A Aronson

DOI:
10.1093/med/9780199764495.003.0009
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date: 11 December 2019

Anaphylaxis has been defined as a “severe, life-threatening generalized or systemic hypersensitivity reaction” (Johansson et al., 2004). It is rapid in onset and may cause death or permanent disability. Early recognition and optimal management are critical. During anesthesia, recognition of anaphylaxis is often delayed because the clinical presentation can mimic other conditions. Epinephrine is the drug of choice in the treatment of anaphylaxis and should be given as early as possible.

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