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Erdheim-Chester Disease 

Erdheim-Chester Disease
Chapter:
Erdheim-Chester Disease
Author(s):

Edward C. Rosenow

DOI:
10.1093/med/9780199756926.003.0101
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date: 18 April 2021

Disease of bone with bilateral symmetric sclerosis of metadiaphyseal region of long bone

35% of patients have lytic lesions

Bone pain in 35% of patients despite nearly 100% bone involvement

Lungs affected in 35% of patients

Multiple organs can be involved—liver, skin, brain, heart or pericardium with infiltration of lipid-laden foamy histiocytes (? variant of histiocytosis X)...

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