Show Summary Details
Page of

Neural Stem Cell Therapy for Temporal Lobe Epilepsy 

Neural Stem Cell Therapy for Temporal Lobe Epilepsy
Neural Stem Cell Therapy for Temporal Lobe Epilepsy

Ashok K. Shetty

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 14 December 2019

The major objective of this chapter is to evaluate the contemporary knowledge and to put forward perspectives concerning the NSC grafting therapy for TLE. Since the efficiency of grafting of neural progenitors obtained from the fetal brain or ES cells are covered in other chapters in this book, this chapter is deliberately confined to studies on the efficacy of NSC grafts in TLE prototypes. The first section will focus on the prospects for preventing or minimizing SRS using NSC grafting procedures that are performed shortly after the initial precipitating injury (IPI), such as SE or a direct excitotoxic lesion. The second section will consider the promise of NSC grafting therapy for restraining seizures and easing cognitive dysfunction when applied shortly after or at prolonged periods after the onset of SE- or kindling- induced TLE. Several critical issues that need to be resolved before initiating the clinical application of NSC grafting therapy for TLE are also discussed.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.