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Disorders relating to use of PCP and hallucinogens 

Disorders relating to use of PCP and hallucinogens
Chapter:
Disorders relating to use of PCP and hallucinogens
Author(s):

Henry David Abraham

DOI:
10.1093/med/9780199696758.003.0064
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date: 23 August 2019

Phencyclidine (PCP, ‘angel dust’) is an arylcyclohexylamine dissociative anaesthetic. It was first abused in the United States in New York and San Francisco in the 1960s, but abuse declined when a broad range of adverse complications was noted. Agents that alter perception and mood without disorientation typify hallucinogenic drugs. They have been known and used for millennia for purposes ranging from magical to medical. Hallucinogenic drugs comprise not so much a single class of compounds, but a multiple classes affecting different neuronal receptors. This chapter looks at the epidemiology, acute physiological effects, and adverse effects of both PCP and hallucinogens. it also covers PCP delirium, PCP-induced psychotic disorder, PCP abuse, dependence, and organic mental disorder, and finally human experimentation with hallucinogens.

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