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Disorders relating to the use of amphetamine and cocaine 

Disorders relating to the use of amphetamine and cocaine
Disorders relating to the use of amphetamine and cocaine

Nicholas Seivewright

and Robert Fung

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date: 04 July 2022

Amphetamine and cocaine are classed as stimulant drugs, although the distinction between stimulants and depressants can be criticized on the grounds that the same drug may have both actions in turn. This does indeed occur with amphetamine and cocaine, but the initial desired effects are increased energy and activity, and elevation in mood. These appear to be mainly due to enhanced central transmission of dopamine and noradrenaline (norepinephrine), with a similar enhancement of serotonin playing a less certain role. This chapter discusses clinical features, classification, diagnosis, epidemiology, aetiology, course and prognosis, treatment and prevention.

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