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End-stage kidney disease 

End-stage kidney disease
Chapter:
End-stage kidney disease
Author(s):

Edwina Brown

, Fliss Murtagh

, Emma Murphy

, and Max Watson

DOI:
10.1093/med/9780199695690.003.0001
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date: 08 December 2019

Chronic kidney disease 2

Causes of kidney failure 4

New patients on dialysis 8

Patients on renal replacement therapy 10

Choice of modality of renal replacement therapy 12

Chronic kidney disease (CKD) is a major public health problem. As the prevalence of diabetes and obesity increases, and as the population ages, the prevalence of CKD will continue to increase. This is reflected not only in the increasing incidence and prevalence of patients with end-stage kidney disease (ESKD) requiring dialysis, but also in the substantial comorbidity found in such patients. Many patients are therefore not going to be suitable for transplantation. Despite the improvements in dialysis care, these patients will experience significant mortality and morbidity and an impaired quality of life....

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