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Frailty: challenges and progress 

Frailty: challenges and progress
Frailty: challenges and progress

Peter Crome

and Frank Lally

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date: 27 September 2021

Key points

Frailty in older people is characterized by deteriorating health and increasing need for support.

Frailty has the features of a ‘geriatric giant’ as originally defined by Isaacs.

The identification of frail older people is important for medical intervention and for strategic planning.

The clinical definition of frailty is still being debated but may include the following aspects:

o a distinct phenotypical profile

o a frailty index defined by the accumulation of deficits

o genetic and biochemical predisposition.

There is no specific treatment for frailty but there are treatments for the diseases that contribute to it.

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