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Under-representation of older people in clinical trials 

Under-representation of older people in clinical trials
Chapter:
Under-representation of older people in clinical trials
Author(s):

Gary H. Mills

DOI:
10.1093/med/9780199689644.003.0016
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date: 23 October 2019

Key points

Older people, often with high levels of co-morbidity and polypharmacy, are increasing in number as the population ages.

Study populations in clinical trials have often not mirrored the population that will consume the drugs or treatments being investigated.

Regulators, ethics committees, and funding bodies must recognize the need for inclusion of older people and the complexities this imposes on investigators.

Across all aspects of medicine, funding for research into how best to safely include older people in clinical trials is vital.

Researchers should not be disadvantaged by designing studies to meet the needs of the age range of patients expected to receive the treatment being investigated; this should include provision for older people.

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