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Focal epilepsy 

Focal epilepsy
Focal epilepsy

Tim Wehner

, Kanjana Unnwongse

, and Beate Diehl

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date: 17 May 2022

This chapter examines the neurophysiology of focal epilepsy. It discusses the principles of EEG source localization. This is followed by a presentation of nonspecific and epileptiform interictal EEG findings and ictal EEG patterns seen in focal epilepsy, along with normal EEG variants that may be mistaken for epileptiform features. Seizure semiologies and ictal and interictal EEG findings in mesial and neocortical temporal lobe epilepsy, orbitofrontal, dorsolateral, and mesial frontal epilepsy, insular epilepsy, and parietal and occipital epilepsy are presented with illustrative case discussions derived from patients investigated for resective epilepsy surgery. A brief discussion of prognosis and treatment strategies for focal epilepsy follows.

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