- Preface
- Abbreviations
- Contributors
- Chapter 1 Nerve, muscle, and neuromuscular junction
- Chapter 2 The motor unit
- Chapter 3 Motor control: spinal and cortical mechanisms
- Chapter 4 Cortical activity: single cell, cell assemblages, and networks
- Chapter 5 Recording of neural signals, neural activation, and signal processing
- Chapter 6 Nerve conduction studies
- Chapter 7 Electromyography
- Chapter 8 Quantitative electromyography
- Chapter 9 Axonal excitability: molecular basis and assessment in the clinic
- Chapter 10 Reflex studies
- Chapter 11 Electroencephalography
- Chapter 12 Intracranial electroencephalographic recordings
- Chapter 13 Magnetoencephalography
- Chapter 14 Transcranial magnetic stimulation
- Chapter 15 Evoked potentials
- Chapter 16 Polysomnography and other investigations for sleep disorders
- Chapter 17 Clinical neurophysiology of the pelvic floor
- Chapter 18 The clinical approach to neurophysiology
- Chapter 19 Focal neuropathies
- Chapter 20 Generalized peripheral neuropathies
- Chapter 21 Disorders of single nerves, roots, and plexuses
- Chapter 22 Neurophysiology in amyotrophic lateral sclerosis and other motor degenerations
- Chapter 23 Clinical aspects of neuromuscular junction disorders
- Chapter 24 Primary muscle diseases
- Chapter 25 Paediatric conditions
- Chapter 26 EMG-guided botulinum toxin therapy
- Chapter 27 Genetic generalized epilepsy
- Chapter 28 Focal epilepsy
- Chapter 29 Syncope
- Chapter 30 Convulsive and non-convulsive status epilepticus
- Chapter 31 Presurgical evaluation for epilepsy surgery
- Chapter 32 Encephalopathy, central nervous system infections, and coma
- Chapter 33 Migraine, stroke, and cerebral ischaemia
- Chapter 34 Electroclinical features of paediatric conditions
- Chapter 35 Sleep disorders
- Chapter 36 Intraoperative monitoring
- Index
(p. 149) Magnetoencephalography
- Chapter:
- (p. 149) Magnetoencephalography
- Author(s):
Paul L. Furlong
, Elaine Foley
, Caroline Witton
, and Stefano Seri
- DOI:
- 10.1093/med/9780199688395.003.0013
For presurgical assessments for resection of an epileptogenic lesion or zone, evaluations over the last 20 years have established magnetoencephalography (MEG) as a valuable tool in routine clinical practice in both adult and paediatric age groups. MEG can accurately localize both ictal and inter-ictal spike sources. MEG yields important additional information in around 30% of patients with epilepsy of suspected neocortical origin, aiding in the modification or extension of invasive measurements. Seizure freedom is most likely to occur when there is concordance between electroencephalogram (EEG) and MEG localization, and least likely to occur when these results are divergent. In some patients, invasive recordings may not be viable or repeatable. In these cases, MEG localization frequently provides additional information for planning surgery. Recent developments in technology for movement compensation and enhanced noise reduction provide optimism for continually improving outcomes of MEG-enhanced presurgical evaluations.
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- Preface
- Abbreviations
- Contributors
- Chapter 1 Nerve, muscle, and neuromuscular junction
- Chapter 2 The motor unit
- Chapter 3 Motor control: spinal and cortical mechanisms
- Chapter 4 Cortical activity: single cell, cell assemblages, and networks
- Chapter 5 Recording of neural signals, neural activation, and signal processing
- Chapter 6 Nerve conduction studies
- Chapter 7 Electromyography
- Chapter 8 Quantitative electromyography
- Chapter 9 Axonal excitability: molecular basis and assessment in the clinic
- Chapter 10 Reflex studies
- Chapter 11 Electroencephalography
- Chapter 12 Intracranial electroencephalographic recordings
- Chapter 13 Magnetoencephalography
- Chapter 14 Transcranial magnetic stimulation
- Chapter 15 Evoked potentials
- Chapter 16 Polysomnography and other investigations for sleep disorders
- Chapter 17 Clinical neurophysiology of the pelvic floor
- Chapter 18 The clinical approach to neurophysiology
- Chapter 19 Focal neuropathies
- Chapter 20 Generalized peripheral neuropathies
- Chapter 21 Disorders of single nerves, roots, and plexuses
- Chapter 22 Neurophysiology in amyotrophic lateral sclerosis and other motor degenerations
- Chapter 23 Clinical aspects of neuromuscular junction disorders
- Chapter 24 Primary muscle diseases
- Chapter 25 Paediatric conditions
- Chapter 26 EMG-guided botulinum toxin therapy
- Chapter 27 Genetic generalized epilepsy
- Chapter 28 Focal epilepsy
- Chapter 29 Syncope
- Chapter 30 Convulsive and non-convulsive status epilepticus
- Chapter 31 Presurgical evaluation for epilepsy surgery
- Chapter 32 Encephalopathy, central nervous system infections, and coma
- Chapter 33 Migraine, stroke, and cerebral ischaemia
- Chapter 34 Electroclinical features of paediatric conditions
- Chapter 35 Sleep disorders
- Chapter 36 Intraoperative monitoring
- Index