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Special considerations in the immunosuppressed patient 

Special considerations in the immunosuppressed patient
Special considerations in the immunosuppressed patient

Anne-Sophie Moreau

, Raphaël Favory

, and Alain Durocher


February 22, 2018: This chapter has been re-evaluated and remains up-to-date. No changes have been necessary.

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date: 11 July 2020

Because of improved treatment of haematological malignancies, autoimmune diseases, and HIV infection, an increasing number of patients are being immunocompromised. Immunosuppression varies according to the underlying disease, and different patterns of complications may be encountered. Among the complications of immunosuppressive treatments, infectious diseases are the most frequently encountered, but drug-related toxicities and secondary neoplasias have to be recognized. Making a rapid diagnosis is the most important step in taking these patients in charge. In such setting, cardiac involvement is severe and often leads to admission to intensive care units. This chapter will focus on the cardiac complications of immunosuppression, from heart transplantation to HIV treatment-related toxicity and cardiac infections.

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