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Pharmacodynamics of addictive substances 

Pharmacodynamics of addictive substances
Pharmacodynamics of addictive substances

Professor David J. Nutt

and Dr Liam J. Nestor

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date: 28 July 2021

Pharmacodynamics refers to the effect of substances on the body

The pharmacodynamics effects of substances take place at receptors

Agonists mimic the effects of neurotransmitters at receptors

Antagonists block the effects of neurotransmitters at receptors

Addictive substances can alter brain pharmacodynamics

Brain pharmacodynamics can be influenced by genetics

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