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Assessing quality-adjusted life years 

Assessing quality-adjusted life years
Assessing quality-adjusted life years

Dr. Henry A. Glick

, Dr. Jalpa A. Doshi

, Dr. Seema S. Sonnad

, and Dr. Daniel Polsky

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date: 04 March 2021

This chapter addresses issues related to the direct and indirect measurement of quality-adjusted life years (QALYs). Specific issues addressed include an updated comparison of four prescored, indirect elicitation instruments (EQ-5D, HUI2, HUI3, and SF-6D), an updated comparison of three direct elicitation methods (standard gamble, time trade-off, and rating scale), and an updated comparison of the prescored indirect elicitation instruments and direct elicitation methods. In addition to comparing the approaches, methods of administration, construction of QALYs by use of preference scores, frequency of elicitation, and responsiveness of instruments are discussed. New sections include material on minimally important differences between the instruments and disease-specific preference-weighted quality of life instruments.

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