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Physiological changes in sleep 

Physiological changes in sleep
Physiological changes in sleep

Sudhansu Chokroverty

, and Sushanth Bhat

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date: 01 December 2020

It is important for clinicians to be conversant with the physiological changes that occur in various organ systems during sleep, and the impact that sleep fragmentation and sleep deprivation have on the normal functioning of these systems. This chapter therefore strives to provide a brief overview of the physiological changes associated with sleep that occur in the central nervous system (CNS), the autonomic nervous system (ANS), the neuromuscular system, the respiratory system (including changes in the control of breathing during various stages of sleep) and cardiovascular systems, the gastrointestinal tract, the endocrine system, and the systems controlling thermoregulation and immune regulation. Additionally, the mechanisms underlying muscle hypotonia in sleep, as well as sleep-related changes in cerebral blood flow and cytokine function are discussed.

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