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An overview of sleep dysfunction in Parkinson disease 

An overview of sleep dysfunction in Parkinson disease
Chapter:
An overview of sleep dysfunction in Parkinson disease
Author(s):

Elisaveta Sokolov

, and K. Ray Chaudhuri

DOI:
10.1093/med/9780199682003.003.0025
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date: 03 April 2020

Disturbances in nocturnal sleep and their consequences during waking in Parkinson disease (PD) were recognized in 1817 by James Parkinson, who described sleep problems in his case series as follows: “His attendants observed, that of late the trembling would sometimes begin in his sleep, and increase until it awakened him: when he always was in a state of agitation and alarm.” Sleep disturbance in PD is complex, with a prevalence of up to 98%, and has been shown to be a key determinant of quality of life. Sleep disturbances in PD are heterogeneous, ranging from insomnia to drug-induced sleep disorders, and now can be assessed by simple validated bedside tools such as the Parkinson’s Disease Sleep Scale (PDSS). Also, sleep, contrary to previous perceptions, can be disordered not just in advanced PD, but also in the pre-motor as well as the untreated states.

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