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Advanced, delayed, free-running, and irregular sleep–wake rhythm disorders 

Advanced, delayed, free-running, and irregular sleep–wake rhythm disorders
Advanced, delayed, free-running, and irregular sleep–wake rhythm disorders

Guy Warman

, and Josephine Arendt

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date: 24 October 2020

This chapter provides an overview of the incidence, presentation, assessment, diagnosis, and management of the four main circadian rhythm sleep disorders: advanced sleep phase disorder (ASPD), delayed sleep phase disorder (DSPD), free-running (non-24-hour) sleep disorder (FRSD), and irregular sleep–wake rhythm disorder (ISWRD). Following a brief discussion of the daily entrainment of the human circadian clock to the light cycle, and the shifting effects of light and melatonin on the clock, each of the four different disorders are considered in turn. The aim of this chapter is to provide a concise overview of the disorders and the potential treatment strategies for each. The chapter is extensively referenced for further information.

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