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Neuroimaging in normal sleep and sleep disorders 

Neuroimaging in normal sleep and sleep disorders
Neuroimaging in normal sleep and sleep disorders

Pierre Maquet

, and Julien Fanielle

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date: 19 October 2020

Functional neuroimaging techniques include methods that probe various aspects of brain function and help derive models of brain organization in health and disease. These techniques can be grouped in two categories. Some are mainly based on electromagnetic signals (electroencephalography, magnetoencephalography), recording brain activity using a large number of sensors with exquisite temporal resolution (usually of the order of a kilohertz) but allowing only indirect characterization of three-dimensional brain activity by resorting to mathematical models. The second type includes different techniques (PET scan, SPECT, MRI, optical imaging) that typically assess metabolic or hemodynamic parameters, with millimeter spatial resolution and usually from the entire brain volume. However, temporal resolution is usually low because it is primarily driven by metabolic processes that unfold in several seconds or minutes. This chapter focuses on this second type, covering the contribution of brain imaging to understanding NREM sleep and REM sleep and also sleep disorders.

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