Show Summary Details
Page of

Opioid pharmacology 

Opioid pharmacology
Chapter:
Opioid pharmacology
Author(s):

Cathy Stannard

, Michael Coupe

, and Anthony Pickering

DOI:
10.1093/med/9780199678075.003.0002
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 21 October 2019

Opioids act through μ‎, κ‎, and δ‎ G-protein coupled receptors. The opioid peptides and receptors form an endogenous analgesic system. Opioid analgesics exert their therapeutic action through μ‎-receptors. Most of the opioid adverse effects are due to μ‎-receptor activation. The rational choice of opioids is governed by their pharmacokinetic profiles and patient’s individual responses to agents. Morphine remains a good starting point to assess the opioid sensitivity of a pain condition.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.