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Mental disorders and the biological substrate of suicide 

Mental disorders and the biological substrate of suicide
Chapter:
Mental disorders and the biological substrate of suicide
Author(s):

Robert D. Goldney

DOI:
10.1093/med/9780199677580.003.0005
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date: 22 August 2019

All mental disorders are associated with a higher risk of suicide. Mood disorders, schizophrenia and substance abuse are strongly associated with suicide. Co-morbidity is common. There is an inherited basis to some suicides. Serotonin and hypothalamic-pituitary-adrenal axis abnormalities are associated with suicide. Biological factors lack specificity for suicide. There is an interaction between genetic susceptibility and the environment.

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