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Introduction to structural pathology 

Introduction to structural pathology
Introduction to structural pathology

David Knott

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date: 19 June 2021

Musculoskeletal conditions are frequently associated with characteristic macroscopic and microscopic changes within the connective tissues, commonly of a degenerative or inflammatory nature. In addition, larger-scale changes in the anatomical structure of body parts, however caused, can lead to altered function and production of symptoms. This chapter considers both aspects of structural pathology with respect to aetiology, recognition, and treatment. Structural abnormalities, both macroscopic and microscopic, do not necessarily result in pain. Likewise, radiological appearances may correlate poorly with clinical symptoms. This chapter therefore stresses the necessary clinical correlation between symptoms, signs, and investigative findings.

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