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Maternal endocrine disorders 

Maternal endocrine disorders
Maternal endocrine disorders

Harini Narayan

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date: 18 June 2021

Endocrine diseases encountered during pregnancy include diabetes, hypo- and hyperthyroidism, Hashimoto’s thyroiditis, prolactinoma, and hyperparathyroidism. Diabetes is the most common pre-existing maternal medical disorder complicating pregnancy with types 1, 2 and gestational diabetes affecting 2–5% of all pregnancies in the UK. This rate is rapidly rising, reflecting global trends. The management of diabetes in pregnancy is based on up-to-date guidelines. The aetiology of thyroid disorders, their diagnosis, treatment and monitoring of response from early pregnancy to after delivery and the effects of poorly corrected thyroid dysfunction are discussed. The link between positive TSH receptor antibodies and transient neonatal hyperthyroidism is highlighted. Individual fact files and care pathways for rarer disorders such as Hashimoto’s thyroiditis, prolactinomas, and hyperparathyroidism outline their effects on materno-fetal outcomes, symptomatology, diagnostic tools and antenatal care including monitoring and assessments. Medical or surgical management options are described. Patient information is provided for each condition.

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