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Maternal malignancy 

Maternal malignancy
Chapter:
Maternal malignancy
Author(s):

Harini Narayan

DOI:
10.1093/med/9780199673643.003.0019
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date: 29 May 2020

Cancer in pregnancy is rare, but with survival rates generally greater than 75% and easier access to fertility treatments, more cancer survivors now consider pregnancy, particularly with greater access to fertility treatments. This chapter presents antenatal management of the most common malignancies with relevance to pregnancy including cancers of the breast, cervix, leukaemia, lymphoma, melanoma, thyroid, ovary, and colon. Multidisciplinary management required when malignancy is diagnosed during pregnancy or pregnancies in cancer survivors, chemo- and radiotherapy, and possible effects on fetal development and long-term outcomes, pregnancy outcomes and prognosis are discussed. The special situations of pregnancy in cancer survivors previously treated with anthracycline as well as conception while on tamoxifen are highlighted. Recommended interval from the end of cancer treatment to conception in individual malignancies is discussed. The fact files, care pathways, and patient information are underpinned by national guidelines and up-to-date literature, including breast cancer addressed as a separate topic.

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