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Maternal haematological and vascular conditions 

Maternal haematological and vascular conditions
Chapter:
Maternal haematological and vascular conditions
Author(s):

Harini Narayan

DOI:
10.1093/med/9780199673643.003.0001
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date: 30 October 2020

This chapter describes the practical multidisciplinary management of a wide range of haematological and vascular conditions in pregnancy. It provides individual fact files, care pathways, and patient information for each condition, based on up-to-date guidelines and best practice evidence, in a format suitable for use in busy clinical settings. Effective management of relatively common conditions including refractory anaemia, thrombophilias, autoimmune conditions, platelet abnormalities, thromboembolism, haemoglobinopathies and red cell antibodies, as well as rarer conditions such as hereditary spherocytosis, haemorrhagic telangiectasia, and thrombotic thrombocytopenic purpura are described. Fact files summarize epidemiology, genetics, pathophysiology and the impact of pregnancy on the condition and vice versa. Care pathways incorporate specific investigations and assessments in each condition from pre-pregnancy through various stages of pregnancy, appropriate referrals to regional/tertiary centres, recommendations regarding essential documentation, communication of key information for intrapartum/ postnatal care and avoidance of unnecessary interventions. Specific patient information is provided for each condition.

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