Show Summary Details
Page of

Genetics of breast and ovarian cancer 

Genetics of breast and ovarian cancer
Chapter:
Genetics of breast and ovarian cancer
Author(s):

Deborah Ruddy

DOI:
10.1093/med/9780199672844.003.0008
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 22 July 2019

Breast cancer is a common disease – ovarian cancer is less common. Mutations in the BRCA1 and BRCA2 genes account for up to10% of all breast and ovarian cancer. Mutations in the BRCA1, BRCA2 and TP53 confer high risks of cancer and genetic testing is offered where there is a 10% or greater chance of a mutation being identified in an individual. Other intermediate penetrance genes and genes associated with syndromic diagnoses have been identified which contribute to hereditary breast and ovarian cancer.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.