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Mineral metabolism 

Mineral metabolism
Mineral metabolism

Helen E. Turner

, Richard Eastell

, and Ashley Grossman

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date: 17 April 2021

This chapter discusses skeletal functions and interactions between the endocrine system and the body’s mineral store. It describes minerals like calcium, phosphate, and magnesium’s regulation by hormones like parathyroid hormone (PTH), vitamin D, and calcitonin. It also investigates mineral-related disorders, such as hypercalcaemia, hypocalcaemia, pseudohypoparathyroidism, and hypophosphataemic rickets, describing their relations with serum PTH, symptoms, genetic causes, and treatment options. Separating disorders of phosphate homeostasis into hypophosphataemia, hyperphosphataemia, and chronic kidney disease, this chapter offers clinical advice on treating mineral–hormonal disorders and describes the symptoms and causes of disruptions in mineral homeostasis.

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