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Clinical presentation of gout 

Clinical presentation of gout
Chapter:
Clinical presentation of gout
Author(s):

Tim L. Jansen

DOI:
10.1093/med/9780199668847.003.0041
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date: 29 May 2020

Gout most typically presents as an acute monoarthritis in characteristic joints (first metatarsophalangeal joint, midfoot and ankle). These acute inflammatory attacks are accompanied by severe pain, swelling, and commonly by erythema over the affected joint. Such attacks are often incapacitating and fully develop within 12 hours resulting in a level of approximately 80% of maximum pain. Such attacks may resolve shortly during the first few gout attacks, but after having had more attacks they may take more than 5 days to resolve. In some patients with persistent hyperuricaemia, tophaceous disease with chronic gouty arthropathy may also occur. In this chapter, characteristics of such a clinical presentation are described.

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