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Typhoid fever: antibiotic treatment choices 

Typhoid fever: antibiotic treatment choices
Typhoid fever: antibiotic treatment choices

Nicholas Feasey

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date: 19 May 2022

Typhoid fever is caused by Salmonella enterica serovar typhi (S. typhi) and is a common cause of fever in a returning traveller. Treatment options have become more complicated with increasing antibiotic resistance including the emergence of isolates with decreased ciprofloxacin susceptibility. Treatment options include the third-generation cephalosporins and azithromycin. The risk of relapse is considered. A case of typhoid fever in a UK resident is presented and the pathophysiology, diagnosis, and management with particular emphasis on antibiotic choices are discussed.

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