- Preface
- Acknowledgements
- Abbreviations
- List of contributors
- Glossary
- Case 1 Squamous cell carcinoma of unknown head and neck primary site
- Case 2 Nasopharyngeal carcinoma
- Case 3 Small cell lung cancer during pregnancy
- Case 4 Breast metastasis from non-small cell lung cancer
- Case 5 Lung cancer in non-smokers
- Case 6 Single brain metastasis from breast cancer
- Case 7 Breast cancer at a nuclear power station
- Case 8 Oesophagus
- Case 9 Stomach
- Case 10 Neuroendocrine tumour
- Case 11 A patient presenting with painless jaundice
- Case 12 Colon cancer
- Case 13 Rectal cancer
- Case 14 Anal cancer
- Case 15 Chromophobe renal cell carcinoma in an adult
- Case 16 Prostate cancer
- Case 17 Testicular cancer
- Case 18 Cervical cancer
- Case 19 Ovarian cancer
- Case 20 Cancer in a renal transplant recipient
- Case 21 Melanoma
- Case 22 Merkel cell carcinoma
- Case 23 Soft tissue sarcoma
- Case 24 Bone sarcoma
- Case 25 Brain tumour
- Case 26 Hodgkin lymphoma
- Case 27 Solitary plasmacytoma
- Case 28 Clinical trial
- Case 29 A jejunal tumour
- Case 30 The role of specialist palliative care
- List of cases by diagnosis
- List of cases by principal clinical features at presentation (case numbers in italics)
- List of cases by aetiological mechanism (case numbers in italics)
- Index
(p. 49) Single brain metastasis from breast cancer
- Chapter:
- (p. 49) Single brain metastasis from breast cancer
- Author(s):
Thankamma Ajithkumar
- DOI:
- 10.1093/med/9780199664535.003.0006
Approximately 10% of patients with breast cancer present with metastatic brain disease. The majority of these patients have multiple brain metastases (78%) and solitary metastasis occurs in 14% of patients and 8% have leptomeningeal disease. While whole brain radiotherapy remains the standard of care in multiple brain metastases, surgery is usually the initial treatment for solitary brain metastasis. However, there is no consensus on the optimal postoperative management of resected solitary metastasis. Although a number of studies report clinical benefits of loco-regional treatment in metastatic breast cancer, there is a lack of consensus on its exact role. There is no standard optimal systemic treatment for metastatic breast cancer and the choice of systemic treatment depends on various patient-related factors such as menopausal status, performance etc, and disease related factors such as HER-2 and hormonal receptor status, tumour burden etc.
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- Preface
- Acknowledgements
- Abbreviations
- List of contributors
- Glossary
- Case 1 Squamous cell carcinoma of unknown head and neck primary site
- Case 2 Nasopharyngeal carcinoma
- Case 3 Small cell lung cancer during pregnancy
- Case 4 Breast metastasis from non-small cell lung cancer
- Case 5 Lung cancer in non-smokers
- Case 6 Single brain metastasis from breast cancer
- Case 7 Breast cancer at a nuclear power station
- Case 8 Oesophagus
- Case 9 Stomach
- Case 10 Neuroendocrine tumour
- Case 11 A patient presenting with painless jaundice
- Case 12 Colon cancer
- Case 13 Rectal cancer
- Case 14 Anal cancer
- Case 15 Chromophobe renal cell carcinoma in an adult
- Case 16 Prostate cancer
- Case 17 Testicular cancer
- Case 18 Cervical cancer
- Case 19 Ovarian cancer
- Case 20 Cancer in a renal transplant recipient
- Case 21 Melanoma
- Case 22 Merkel cell carcinoma
- Case 23 Soft tissue sarcoma
- Case 24 Bone sarcoma
- Case 25 Brain tumour
- Case 26 Hodgkin lymphoma
- Case 27 Solitary plasmacytoma
- Case 28 Clinical trial
- Case 29 A jejunal tumour
- Case 30 The role of specialist palliative care
- List of cases by diagnosis
- List of cases by principal clinical features at presentation (case numbers in italics)
- List of cases by aetiological mechanism (case numbers in italics)
- Index