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Brain tumour 

Brain tumour
Chapter:
Brain tumour
Author(s):

Thankamma Ajithkumar

DOI:
10.1093/med/9780199664535.003.0025
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date: 18 August 2019

Brain tumours are characterised by a wide spectrum of pathological types and clinical behaviour. In adults, high-grade gliomas account for the vast majority of brain tumours. In spite of multimodality treatment, the overall prognosis remains poor. Studies suggest that there is a correlation between the extent of surgical resection and survival in high-grade brain tumours. Concomitant chemoradiotherapy followed by adjuvant temozolomide is the standard treatment for glioblastoma. The role of addition of chemotherapy to radical radiotherapy in grade 3 tumours is yet to be proved. Patients with poor performance status and/or significant neurological deficits are treated with short-course palliative radiotherapy or best supportive care.

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