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Nasopharyngeal carcinoma 

Nasopharyngeal carcinoma
Chapter:
Nasopharyngeal carcinoma
Author(s):

Suat W. Loo

and Tom Roques

DOI:
10.1093/med/9780199664535.003.0002
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date: 20 August 2019

The majority of patients with nasopharyngeal carcinoma present with stage III or IV disease. Radiotherapy to a curative dose with concurrent platinum-based chemotherapy is the standard of care in the management of this group of patients. Despite this, a significant proportion will develop local tumour recurrence. Early-stage local recurrences can be managed with salvage nasopharyngectomy, intracavitary brachytherapy or interstitial implants. In those with locally advanced recurrent tumours, re-irradiation with external-beam radiotherapy represents the only potentially curative treatment option. With careful patient selection, long-term survival can be achieved.

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