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Testicular cancer 

Testicular cancer
Chapter:
Testicular cancer
Author(s):

Susanna Alexander

DOI:
10.1093/med/9780199664535.003.0017
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date: 26 February 2021

Testicular cancer has a high cure rate of approximately 95%. The typical presentation is in young adults aged 15-35 years. Orchiectomy is the standard of care and performed firstly unless there is life-threatening metastastic disease, and clinical diagnosis can be made by raised tumour markers. Postoperative treatment is based on the stage of the disease and histology (seminoma vs. non-seminoma). Residual masses can occur after chemotherapy in advanced clinical stages. These masses represent either residual disease or non-viable tissue. PET scan has in important role in predicting presence of viable disease in residual masses of in seminoma, especially if the mass is >3 cm. Because of the false negative results, PET has no established role in non-seminomatous residual disease.

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