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Rectal cancer 

Rectal cancer
Chapter:
Rectal cancer
Author(s):

Debashis Biswas

and Thankamma Ajithkumar

DOI:
10.1093/med/9780199664535.003.0013
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date: 18 August 2019

Recent advances in colonic surgery have a major impact on survival for patients with localised rectal cancer. Identification of patients at higher risk of local failure is important in selecting patients for pre-operative radiotherapy/chemo-radiotherapy. Short-course preoperative radiotherapy is used in operable rectal cancer to reduce the risk of local recurrence. In patients with T3-4 or node-positive rectal cancer, preoperative chemoradiotherapy results in fewer local recurrences and more favourable long-term toxicity compared with postoperative treatment.

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