Show Summary Details
Page of

Epilepsy and related disorders 

Epilepsy and related disorders
Chapter:
Epilepsy and related disorders
Author(s):

Dewi Schrader

, Neda Bernasconi

, and Andrea Bernasconi

DOI:
10.1093/med/9780199664092.003.0012
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 09 July 2020

The two most common causes of drug-resistant epilepsy are mesial temporal sclerosis and focal cortical dysplasia. Structural magnetic resonance imaging (MRI) is the most useful technique for delineating the underlying cause of seizures, particularly when combined with recent post-processing methods that further increase our ability to reveal subtle lesions. In cases where structural MRI is unrevealing or discordant with electroclinical information, functional studies may play an adjunctive role by helping to direct a focused re-evaluation of the structural MRI or the placement of intracranial electrodes. Besides playing a pivotal role in the management of patients with drug-resistant seizures, advances in neuroimaging have significantly deepened our understanding of epilepsy, including patients with seizures that are not due to focal lesions, such as in idiopathic generalized epilepsy, and provide important information on the pathogenesis of this condition, as well as the effects of recurrent seizures on the brain.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.