- Section 1 The development of the discipline of public health
- Section 2 Determinants of health and disease
- Section 3 Public health policies, law, and ethics
- Section 4 Information systems and sources of intelligence
- Section 5 Epidemiological and biostatistical approaches
- Section 6 Social science techniques
- Section 7 Environmental and occupational health sciences
- Section 8 Major health problems
- 8.1 Epidemiology and prevention of cardiovascular disease
- 8.2 Cancer epidemiology and public health
- 8.3 Chronic obstructive pulmonary disease and asthma
- 8.4 Obesity
- 8.5 Physical activity and health
- 8.6 Diabetes mellitus
- 8.7 Public mental health and suicide
- 8.8 Dental public health
- 8.9 Musculoskeletal disorders
- 8.10 Neurological diseases, epidemiology, and public health
- 8.11 Infectious diseases and prions
- 8.12 Sexually transmitted infections
- 8.13 HIV/acquired immunodeficiency syndrome
- 8.14 Tuberculosis
- 8.15 Malaria
- 8.16 Chronic hepatitis and other liver disease
- 8.17 Emerging and re-emerging infections
- 8.18 Bioterrorism
- Section 9 Prevention and control of public health hazards
- Section 10 Public health needs of population groups
- Section 11 Public health functions
(p. 1175) Chronic hepatitis and other liver disease
- Chapter:
- (p. 1175) Chronic hepatitis and other liver disease
- Author(s):
Pierre Van Damme
, Tinne Lernout
, Koen Van Herck
, Rui T. Marinho
, Raymundo Paraná
, and Daniel Shouval
- DOI:
- 10.1093/med/9780199661756.003.0216
Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are major risk factors in the development of hepatocellular carcinoma (HCC) either by inducing cirrhosis or by direct oncogenic effects, representing a major burden worldwide. Around 400 million people are chronically infected with HBV or HCV and approximately 1 million people die each year (~2.7% of all deaths) from causes related to viral hepatitis, most commonly cirrhosis and HCC. Alcohol consumption is responsible for increased illness and death and is associated with an increased risk of a number of cancers. Non-alcoholic fatty liver disease and non-alcoholic steatohepatitis are chronic liver diseases associated with the metabolic syndrome. This tends to take epidemic proportions in the Western population, and to constitute a major health problem in the near future. On the other hand, obesity seems to be also a strong oncogenic condition, in particular for HCC.
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- Section 1 The development of the discipline of public health
- Section 2 Determinants of health and disease
- Section 3 Public health policies, law, and ethics
- Section 4 Information systems and sources of intelligence
- Section 5 Epidemiological and biostatistical approaches
- Section 6 Social science techniques
- Section 7 Environmental and occupational health sciences
- Section 8 Major health problems
- 8.1 Epidemiology and prevention of cardiovascular disease
- 8.2 Cancer epidemiology and public health
- 8.3 Chronic obstructive pulmonary disease and asthma
- 8.4 Obesity
- 8.5 Physical activity and health
- 8.6 Diabetes mellitus
- 8.7 Public mental health and suicide
- 8.8 Dental public health
- 8.9 Musculoskeletal disorders
- 8.10 Neurological diseases, epidemiology, and public health
- 8.11 Infectious diseases and prions
- 8.12 Sexually transmitted infections
- 8.13 HIV/acquired immunodeficiency syndrome
- 8.14 Tuberculosis
- 8.15 Malaria
- 8.16 Chronic hepatitis and other liver disease
- 8.17 Emerging and re-emerging infections
- 8.18 Bioterrorism
- Section 9 Prevention and control of public health hazards
- Section 10 Public health needs of population groups
- Section 11 Public health functions